It is the first dose that has really worked for me. At first I thought it was gonna be a great fail, because I've tried MultipleO, Orgasm and Out-of-body, and none of them made me feel nothing. With this one I felt very relaxed (with the others I surprised myself feeling quite rigid and tense) and I felt my body very warm (not sweaty, just a nice warming) and sometimes I felt a little tingling in my chest. This is a medley of different sensations that will not disappoint you. I will try more doses for sure.